Gregory Sempowski, PhD - Core Director
The Immune Monitoring Core for RadCCORE is comprised of technologies and services offered by two service laboratories within the Duke Human Vaccine Institute (DHVI): the Flow Cytometry Facility and the Immune Reconstitution and Biomarker Facility. In this competitive renewal (y6-10) we have focused the scope of Core offerings based on project utilization and future needs. The Immune Monitoring Core (Core C) will centrally provide RadCCORE investigators with high quality, state-of-the-art cell sorting, multiplex cytokine/chemokine assays, and T cell receptor gene expression analysis for their basic and applied research efforts. In addition to providing these services, the Core will be instrumental in developing new methodologies and making them available to RadCCORE Investigators. Administrative oversight for the Core will institute a charge-back mechanism for services provided in excess of budget to remain revenue neutral and financially compliant. In addition, the Core will utilize our innovative FacMan-Facility Manager web application created by the Duke Human Vaccine Institute to schedule/request core work, maintain accurate and compliant records of uses and projects, and invoice for services rendered.